Pigmented Spindle Cell Nevus of Reed Dermatopathology

Dermoscopy of Pigmented Spitz and Reed Nevi Dermatology JAMA Dermatology The JAMA Network

The clinical-dermatoscopic-histological correlation of excised Spitz/Reed nevi revealed overlapping histopathological features among lesions displaying distinct dermatoscopic patterns ( Figures 1 - 3 ). Among lesions with histopathological atypia (16/47, 34.0%), all dermatoscopic patterns were represented, although the atypical/multicomponent.

Dermatoscopic patterns of Reed nevus. Starburst pattern in which black,... Download Scientific

In contrast to Spitz nevus, the indicators of a congenital origin of Reed nevus are poor. The outstanding reports on agminated or systematized Reed nevi, or Reed nevus as constituent of a combined nevus, rather suggest a histogenetic event compatible with what is regarded to be a truly acquired melanocytic nevus and might represent another clue.

Nevus definition, types, diagnosis & nevus treatment

Reed nevus is composed histologically of elongated spindle-shaped and nevoid cells with a benign biologic behavior. Histopathological features in common with Spitz nevi and in contrast with malignant melanoma include a relatively small size, lesion symmetry, uniformity of cell type, good circumscription, and maturation of cells from superficial.

Pigmented Spindle Cell Nevus of Reed Dermatopathology

'Nevus, Reed' published in 'Dermatopathology' Pigmented spindle cell nevus is a sharply demarcated and symmetrical melanocytic lesion characterized by a florid and cellular junctional component and marked melanin pigmentation (Fig. 1).The junctional aspect is composed of large and prominent nests containing uniform, spindled melanocytes arranged in fascicles with a characteristic vertical.

Starburst dermoscopic pattern of Reed nevus Download Scientific Diagram

Reed nevus is considered a pigmented variant of Spitz nevus. It usually appears during childhood, adolescence or early adulthood, and commonly appears on the lower limbs of female patients. After 6 months of rapid growth, Reed nevus tends to show no more enlargements over time. The starburst pattern is the dermatoscopic hallmark of Reed nevus.

Dermoscopy of Pigmented Spitz and Reed Nevi The Starburst Pattern Dermatology JAMA

The Spitz naevus (syn. spindle cell naevus, epithelioid cell naevus, juvenile melanoma) is a variant of a compound naevus and is most commonly seen in children . The pigmented spindle cell naevus of Reed (PSCNOR) is a variant of a compound or occasionally a junctional naevus. There is debate as to whether the PSCNOR is an entity in its own.

Reed nevus on the finger (A) Clinical features of the lesion. (B)... Download Scientific Diagram

A Reed nevus is a dark brown or black, raised, dome-shaped mole that most often affects women. These moles can grow quickly and may be mistaken for melanoma. These moles can grow quickly and may.

Figure 1 from Pigmented Spindle Cell Nevus of Reed of the Eyelid Semantic Scholar

Spitz naevus is classified as classic, pigmented, or spindle cell tumour of Reed. The classic Spitz naevus is typically a dome-shaped red, reddish-brown papule. A pigmented Spitz naevus is a tan or brown papule or nodule. A pigmented spindle cell tumour of Reed is a bluish or black papule. There are clinical features in common for all three.

Dermpath Made Simple Neoplastic Spitz Nevus and Reed Nevus

Pigmented spindle cell nevus (PSCN) of Reed is a morphologic variant of Spitz and may be very diagnostically challenging, having histologic features concerning for melanoma. Their occurrence in younger patients, lack of association to sun exposure, and rapid early growth phase similar to Spitz nevi suggest fusions may also play a significant.

Dermoscopy Made Simple Reed Nevus

Symmetric with cytologic maturation. Nests and fascicles of spindled melanocytes along dermoepidermal junction and within dermal papillae. May be junctional or compound. Expansive, not infiltrative growth pattern. Extends no deeper than reticular dermis. Nevus cells typically contain abundant melanin pigment, may be associated with melanophages.

Evolution of Reed Nevi Dermoscopic Pattern in Childhood Dermatology JAMA Dermatology JAMA

Clinically, pigmented Spitz/Reed nevi are brown to black, flat to slightly elevated, symmetrical lesions showing a relative preference for certain locations, including face, limbs and buttocks. The most relevant and peculiar feature is the starburst pattern seen by dermoscopy. This is typified by multiple streaks of pigmentation or large.

Reed Nevus (Pigmented Spindle Cell Nevus) in an 11MonthOld Japanese Infant

However, to date, many textbooks or atlases of dermatology or histopathology assert that Reed nevus is a variant of Spitz nevus [4,6,21-25]. According to Argenziano et al, a dermatopathologic distinction between pigmented Spitz and Reed nevus is difficult, not reproducible and maybe clinically useless.

Dermpath Made Simple Neoplastic Spitz Nevus and Reed Nevus

Pigmented spindle cell nevus is a benign melanocytic lesion that was initially described in 1975 by Reed et al. It is generally found on the trunk or lower extremities of young women. Most authors consider it to be a variant of Spitz nevus. The main concern with these lesions remains their propensity to mimic melanoma both clinically and histologically.

Pigmented Spindle Cell Nevus of Reed Dermatopathology

The Reed Nevus or pigmented spindle cell nevus (PSCN) was first described by Reed et al. in 1975 . Its designation as a separate entity vs. a SN variant remains controversial, but is currently considered by the 2018 WHO Classification to be a "distinct variant of Spitz naevus.".

Pigmented Spindle Cell Nevus of Reed Dermatopathology

Reed nevus (also known as pigmented spindle cell nevus of Reed) is an acquired, benign, melanocytic lesion most frequently classified as a variant of a Spitz nevus. A Reed nevus typically presents as an asymptomatic, single, 2-8 mm, dark brown to black macule or papule on the lower extremities of young adults. The lesion may also be found in.

Dermpath Made Simple Neoplastic Spitz Nevus and Reed Nevus

Update on dermoscopy of Spitz/Reed naevi and management guidelines by the International Dermoscopy Society Br J Dermatol. 2017 Sep;177(3):645-655. doi: 10.1111/bjd.15339.. Nevus, Epithelioid and Spindle Cell / pathology Nevus, Epithelioid and Spindle Cell / therapy*.